Welcome to the ultimate guide on making the perfect Mac And Cheese Meatloaf Casserole! This hearty and comforting dish is a favorite among many, and for good reason. It’s packed with flavor, easy to make, and perfect for those chilly evenings when you need something warm and satisfying. Whether you’re a seasoned cook or a beginner in the kitchen, this recipe will have you whipping up a delicious Mac And Cheese Meatloaf Casserole in no time.
(Note: the recipe card directly below.PDF )
Why You’ll Love This Mac And Cheese Meatloaf Casserole
There are so many reasons to love this Mac And Cheese Meatloaf Casserole recipe. First and foremost, it’s incredibly flavorful. The combination of tender meatloaf, creamy mac and cheese, and rich sauce creates a symphony of tastes that will have your taste buds dancing. Plus, it’s a one-pot wonder, which means less cleanup for you!
But that’s not all. This casserole is also incredibly versatile. You can easily customize it to suit your preferences or dietary needs. Whether you want to add more vegetables, swap out the beef for chicken, or make it vegetarian, the options are endless.
And let’s not forget about the leftovers. This casserole tastes even better the next day, making it the perfect meal prep option. Just reheat and enjoy!

Ingredients for Mac And Cheese Meatloaf Casserole
Here’s what you’ll need to make this delicious Mac And Cheese Meatloaf Casserole:
- 1 lb ground beef
- 1 onion, diced
- 2 cloves garlic, minced
- 1 bell pepper, diced
- 2 cups elbow macaroni
- (Note: the full ingredients list, including measurements, is provided in the recipe card directly below.)
Variations
One of the best things about this Mac And Cheese Meatloaf Casserole recipe is how easy it is to customize. Here are a few variations you might want to try:
- Vegetarian Mac And Cheese Casserole: Swap out the ground beef for a plant-based alternative or add extra vegetables like mushrooms and zucchini.
- Spicy Mac And Cheese Casserole: Add a pinch of cayenne pepper or a diced jalapeño for a kick of heat.
- Creamy Mac And Cheese Casserole: Stir in a cup of heavy cream or milk before serving for a creamier texture.
- Slow Cooker Mac And Cheese Casserole: Throw all the ingredients into a slow cooker and let it simmer for 6-8 hours on low.
How to Make Mac And Cheese Meatloaf Casserole
Making Mac And Cheese Meatloaf Casserole is a breeze. Here’s a step-by-step guide to help you along the way:
- Preheat the Oven: Preheat your oven to 375°F (190°C).
- Cook the Macaroni: Cook the elbow macaroni according to package instructions until al dente. Drain and set aside.
- Brown the Beef: In a large skillet, heat the olive oil over medium heat. Add the ground beef and cook until browned, about 5-7 minutes. Drain any excess fat.
- Sauté the Vegetables: Add the onion, garlic, and bell pepper to the skillet. Cook until the vegetables are softened, about 5 minutes.
- Combine the Ingredients: In a large bowl, combine the cooked macaroni, browned beef, sautéed vegetables, shredded cheese, cream of mushroom soup, milk, salt, black pepper, paprika, and Italian seasoning. Mix well.
- Assemble the Casserole: Transfer the mixture to a greased 9×13-inch baking dish. Spread it out evenly and top with extra shredded cheese if desired.
- Bake: Bake in the preheated oven for 25-30 minutes, or until the casserole is bubbly and the top is golden brown.
- Serve: Let the casserole cool for a few minutes, then garnish with chopped parsley and serve.

Tips and Tricks
Here are a few tips and tricks to make your Mac And Cheese Meatloaf Casserole even better:
- Use Fresh Ingredients: Whenever possible, use fresh vegetables and herbs for the best flavor.
- Adjust the Seasoning: Taste the casserole before baking and adjust the seasoning as needed. You might want to add more salt, pepper, or other spices to suit your taste.
- Add a Crunchy Topping: For a little extra texture, sprinkle some breadcrumbs or crushed crackers on top before baking.
- Freeze Leftovers: This casserole freezes beautifully. Just let it cool completely, then transfer it to an airtight container and freeze for up to 3 months.
How to Serve
Mac And Cheese Meatloaf Casserole is a hearty meal on its own, but it’s even better with a few sides. Here are some serving suggestions:
- Salad: Pair with a simple green salad for a balanced meal.
- Bread: Serve with a crusty loaf of bread or warm dinner rolls for dipping.
- Vegetables: Add a side of steamed or roasted vegetables for extra nutrition.
Make Ahead and Storage
This Mac And Cheese Meatloaf Casserole is perfect for meal prepping. Here’s how to make it ahead and store it:
- Make Ahead: You can assemble the casserole up to 24 hours in advance. Just cover it with plastic wrap and store it in the refrigerator until ready to bake.
- Reheat: Reheat the casserole in the oven at 350°F (175°C) for 20-25 minutes, or until warmed through. You can also reheat it in the microwave.
- Freeze: To freeze, let the casserole cool completely, then transfer it to an airtight container. Freeze for up to 3 months. Thaw overnight in the refrigerator before reheating.
FAQs
Can I make this casserole in a slow cooker?
Yes! Just throw all the ingredients into a slow cooker and let it simmer for 6-8 hours on low.
Can I use chicken instead of beef?
Absolutely. You can swap out the ground beef for ground chicken or turkey.
Is this casserole gluten-free?
Yes, this casserole is gluten-free. Just make sure to check the labels of your ingredients to ensure they are certified gluten-free.
Can I freeze this casserole?
Yes, this casserole freezes beautifully. Just let it cool completely, then transfer it to an airtight container and freeze for up to 3 months.
How can I make this casserole spicier?
Add a pinch of cayenne pepper or a diced jalapeño for a kick of heat.
Can I add more vegetables?
Of course! Feel free to add extra vegetables like mushrooms, zucchini, or spinach.
Conclusion
And there you have it—the ultimate guide to making delicious Mac And Cheese Meatloaf Casserole. This hearty and comforting dish is sure to become a favorite in your household. Whether you’re looking for a cozy meal on a chilly evening or a satisfying lunch to meal prep, this casserole has you covered. So, grab your ingredients and get cooking! Your taste buds will thank you.
Print
Mac And Cheese Meatloaf Casserole
- Prep Time: 20 minutes
- Cook Time: 30 minutes
- Total Time: 50 minutes
- Yield: 6 servings 1x
- Category: recipe
- Method: Baking
- Cuisine: American
Description
Welcome to the ultimate guide on making the perfect Mac And Cheese Meatloaf Casserole! This hearty and comforting dish is a favorite among many, and for good reason. It’s packed with flavor, easy to make, and perfect for those chilly evenings when you need something warm and satisfying. Whether you’re a seasoned cook or a beginner in the kitchen, this recipe will have you whipping up a delicious Mac And Cheese Meatloaf Casserole in no time.
Ingredients
Here’s what you’ll need to make this delicious Mac And Cheese Meatloaf Casserole:
- 1 lb ground beef
- 1 onion, diced
- 2 cloves garlic, minced
- 1 bell pepper, diced
- 2 cups elbow macaroni
- 2 cups shredded cheddar cheese
- 1 can (10.5 oz) cream of mushroom soup
- 1/2 cup milk
- 1 tsp salt
- 1/2 tsp black pepper
- 1 tsp paprika
- 1 tsp Italian seasoning
- 1 tbsp olive oil
- Optional toppings: chopped parsley, extra shredded cheese
Instructions
Making Mac And Cheese Meatloaf Casserole is a breeze. Here’s a step-by-step guide to help you along the way:
- Preheat the Oven: Preheat your oven to 375°F (190°C).
- Cook the Macaroni: Cook the elbow macaroni according to package instructions until al dente. Drain and set aside.
- Brown the Beef: In a large skillet, heat the olive oil over medium heat. Add the ground beef and cook until browned, about 5-7 minutes. Drain any excess fat.
- Sauté the Vegetables: Add the onion, garlic, and bell pepper to the skillet. Cook until the vegetables are softened, about 5 minutes.
- Combine the Ingredients: In a large bowl, combine the cooked macaroni, browned beef, sautéed vegetables, shredded cheese, cream of mushroom soup, milk, salt, black pepper, paprika, and Italian seasoning. Mix well.
- Assemble the Casserole: Transfer the mixture to a greased 9×13-inch baking dish. Spread it out evenly and top with extra shredded cheese if desired.
- Bake: Bake in the preheated oven for 25-30 minutes, or until the casserole is bubbly and the top is golden brown.
- Serve: Let the casserole cool for a few minutes, then garnish with chopped parsley and serve.
Notes
Here are a few tips and tricks to make your Mac And Cheese Meatloaf Casserole even better:
- Use Fresh Ingredients: Whenever possible, use fresh vegetables and herbs for the best flavor.
- Adjust the Seasoning: Taste the casserole before baking and adjust the seasoning as needed. You might want to add more salt, pepper, or other spices to suit your taste.
- Add a Crunchy Topping: For a little extra texture, sprinkle some breadcrumbs or crushed crackers on top before baking.
- Freeze Leftovers: This casserole freezes beautifully. Just let it cool completely, then transfer it to an airtight container and freeze for up to 3 months.
Nutrition
- Serving Size: 1 serving
- Calories: 450
- Sugar: 5g
- Sodium: 800mg
- Fat: 25g
- Carbohydrates: 30g
- Fiber: 2g
- Protein: 25g
Keywords: Mac And Cheese Meatloaf Casserole